Sideropenia

Last update: June 10, 2025

Summary about Disease


Sideropenia, commonly known as iron deficiency, is a condition where the body doesn't have enough iron. Iron is essential for producing hemoglobin, a protein in red blood cells that carries oxygen throughout the body. This deficiency can lead to a variety of health problems.

Symptoms


Fatigue

Weakness

Pale skin

Shortness of breath

Headache

Dizziness or lightheadedness

Cold hands and feet

Brittle nails

Unusual cravings for non-nutritive substances like ice, dirt, or clay (pica)

Poor appetite, especially in infants and children

Causes


Inadequate dietary iron intake: Not consuming enough iron-rich foods.

Malabsorption: Conditions that impair iron absorption in the digestive tract (e.g., celiac disease, Crohn's disease, gastric bypass surgery).

Blood loss: Chronic blood loss from menstruation, gastrointestinal bleeding (ulcers, colon polyps, cancer), frequent blood donation.

Increased iron requirements: Pregnancy, breastfeeding, periods of rapid growth (infancy, adolescence).

Certain medications: Such as NSAIDs, which can increase the risk of gastrointestinal bleeding.

Medicine Used


Iron supplements: Ferrous sulfate, ferrous gluconate, ferrous fumarate (oral iron supplements are the most common treatment).

Intravenous iron: Iron sucrose, iron dextran, ferric carboxymaltose (used when oral iron is poorly tolerated or ineffective, or in cases of severe iron deficiency).

Vitamin C: May be recommended alongside iron supplements to enhance iron absorption.

Addressing underlying causes: Medications or treatments to stop blood loss (e.g., treatment for ulcers, surgery for polyps).

Is Communicable


No, sideropenia is not communicable. It is a deficiency disease and not caused by an infectious agent.

Precautions


Dietary changes: Consume iron-rich foods (red meat, poultry, fish, beans, lentils, spinach, fortified cereals).

Improve iron absorption: Eat iron-rich foods with vitamin C-rich foods. Avoid consuming iron with calcium-rich foods, coffee, or tea.

Address underlying conditions: Treat any conditions that contribute to blood loss or malabsorption.

Supplementation (with medical advice): Take iron supplements as prescribed by a doctor.

Monitoring: Regular blood tests to monitor iron levels, especially during pregnancy or for individuals at risk.

How long does an outbreak last?


Sideropenia is not an outbreak. Recovery time depends on the severity of the deficiency and the individual's response to treatment. It can take several weeks to months of iron supplementation to replenish iron stores.

How is it diagnosed?


Complete Blood Count (CBC): Measures red blood cell count, hemoglobin, and hematocrit levels.

Serum Iron: Measures the amount of iron in the blood.

Serum Ferritin: Measures iron stores in the body.

Total Iron Binding Capacity (TIBC): Measures the blood's capacity to bind iron.

Transferrin Saturation: Indicates the percentage of transferrin (a protein that carries iron) that is saturated with iron.

Peripheral Blood Smear: Microscopic examination of blood cells to assess their size and shape.

Timeline of Symptoms


The onset and progression of symptoms vary depending on the severity of the iron deficiency.

Early stages: Fatigue, weakness, and pale skin may be mild and easily overlooked.

Moderate stages: Symptoms become more pronounced, including shortness of breath, headache, dizziness, and brittle nails.

Severe stages: Symptoms are debilitating and can include chest pain, rapid heartbeat, and pica.

Important Considerations


Underlying causes: Identifying and treating the underlying cause of iron deficiency is crucial for long-term management.

Pregnancy: Iron deficiency is common during pregnancy due to increased iron requirements and should be closely monitored and treated.

Children: Iron deficiency can impair growth and development in children.

Interactions: Iron supplements can interact with other medications.

Side effects: Iron supplements can cause side effects, such as constipation, nausea, and stomach pain.

Follow-up: Regular monitoring of iron levels is important to ensure effective treatment and prevent recurrence.