Adenomyomatosis: Causes, Symptoms, Diagnosis, and Treatment


Adenomyomatosis is a benign condition that affects the gallbladder. It involves the abnormal growth of the gallbladder wall, leading to the formation of small pouches known as Rokitansky-Aschoff sinuses. While generally harmless, adenomyomatosis can sometimes cause discomfort and may require medical attention. In this article, we will explore the causes, symptoms, diagnosis, and treatment of adenomyomatosis, shedding light on this gallbladder condition.


Adenomyomatosis is a non-cancerous condition characterized by the proliferation of the gallbladder wall. It can lead to the development of small outpouchings called Rokitansky-Aschoff sinuses within the gallbladder. These sinuses can accumulate bile and cholesterol crystals, creating small polyp-like structures. Adenomyomatosis can affect people of all ages, but it is more common in individuals over 50 years old.


Many individuals with adenomyomatosis may not experience any symptoms, and the condition may be incidentally discovered during imaging tests for unrelated reasons. However, some people may experience mild symptoms, such as:

  • Mild abdominal pain or discomfort, typically in the upper right quadrant
  • Episodic pain that comes and goes
  • Indigestion or bloating


The exact cause of adenomyomatosis is not well understood. It is believed to be related to changes in the gallbladder wall over time. Certain risk factors may contribute to its development, including:

  • Age: Adenomyomatosis is more common in individuals over 50 years old.
  • Gender: It tends to affect women more frequently than men.
  • Gallstones: The presence of gallstones may be associated with an increased risk of adenomyomatosis.


Diagnosing adenomyomatosis often involves imaging tests, such as:

  • Ultrasound: This non-invasive test can visualize the gallbladder and detect the presence of Rokitansky-Aschoff sinuses.
  • Magnetic Resonance Cholangiopancreatography (MRCP): MRCP provides detailed images of the bile ducts and gallbladder, aiding in the diagnosis of adenomyomatosis.


In most cases, adenomyomatosis does not require specific treatment, especially if it does not cause significant symptoms. However, if symptoms are bothersome, treatment options may include:

  • Conservative Management: Over-the-counter pain relievers may help manage mild pain or discomfort.
  • Dietary Changes: Avoiding certain trigger foods may alleviate indigestion or bloating.
  • Cholecystectomy: In severe cases or when symptoms are persistent, surgical removal of the gallbladder (cholecystectomy) may be considered.


Adenomyomatosis is a benign condition characterized by the abnormal growth of the gallbladder wall and the formation of small pouches called Rokitansky-Aschoff sinuses. Although often asymptomatic, some individuals may experience mild abdominal discomfort. Diagnosis is typically made through imaging tests, and treatment is generally not required unless symptoms are problematic. If you suspect you have adenomyomatosis or experience persistent abdominal discomfort, seek medical advice for proper evaluation and management.

Disclaimer: This article is for informational purposes only and should not replace professional medical advice. Always consult with a qualified healthcare provider for accurate diagnosis and treatment options specific to your condition.